Our Science

We’re working on one of the most difficult and meaningful challenges of our time. If that sounds like your ideal workplace, we’d like to hear from you.

HSC Reprogramming

Over 90% of our body’s cells are blood cells. Made in the bone marrow by hematopoietic stem cells (HSCs), we can replace these cells through bone marrow transplantation. We aim to produce large numbers of rejuvenated HSCs for transplantation.

Autophagy Enhancement

Autophagy is a fundamental cellular process involving degradation and recycling of their components, helping to clear and prevent accumulation of protein aggregates and damaged biomolecules. The program aims to boost autophagy, starting with a small molecule inducer.

Microglia Therapeutics

We have replicated and expanded upon the rejuvenating effects of plasmapheresis in academic literature. We are now pursuing potent effects that we have observed in the brain, with the aim of creating a more scalable therapy than apheresis.

In Vivo Reprogramming

We are developing safe gene therapies to slow down and reverse aging in vivo aiming to prevent, stop, or revert age-related diseases.

T Cell Reprogramming

T cells are part of our adaptive immune system, fighting pathogens and cancer cells. By rejuvenating T cells, we hope to revert sick cell states to develop the next generation of T cell therapies for diseases like cancer.

Join Us

Interested in extending healthy human lifespan?

See open roles